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We believe the magnitude of weight loss, robust reductions in triglycerides, LDL (low-density lipoprotein) cholesterol and blood pressure, together with the safety profile observed in this trial, could potentially differentiate pemvidutide from the other incretin-based therapies, said Vipin K

The weight loss from GLP-1 agonism derives from appetite suppression and possibly enhanced satiety signals

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doi: 10.1021/acsomega.2c02389 58 JauregiP.Esnal-YeregiL.LabidiJ

Our bodies aren't "resilient" enough to handle the new weight and are ready to bounce back to the old weight at any moment

The reference compound, which does not cross the BBB, is used to determine the amount of test compound injected