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A phase 2 study (MARIPOSA randomized trial) demonstrated that, in patients with OSA, administration of aroxybutynin (an antimuscarinic agent) combined with atomoxetine (a norepinephrine reuptake inhibitor) led to modest but significant reductions in AHI (AHI reduction of 5.9 events/hour greater than placebo) over a 4-week period, though the use of atomoxetine was also associated with a reduction of total sleep time by approximately 21 min

One group received NAC, while the other group received a placebo

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Difference Between L-Arginine and L-Carnitine Definition L-arginine is an amino acid derivative that helps the body build proteins, while L-carnitine is a naturally occurring amino acid derivative that helps in the production of energy by transporting fatty acids into cells mitochondria