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This article examines the theoretical mechanisms, reviews available clinical data, and clarifies why GLP-1 agonists are not recommended for rheumatoid arthritis treatment

Studies have shown that both IMAT and specific IMCL species are positively associated with skeletal muscle insulin resistance [29-35], a key defect in T2DM [36]

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Third, although the study adjusted for multiple covariates, such as age, gender, BMI, and smoking, there may still be unmeasured confounding factors that could affect the results