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The main results of the trial were as follows: Patients taking the maximum dose (12mg) lost an average of 70.3 lbs (28.3%) over 80 weeks Participants with a baseline body mass index (BMI) of 35 or above lost an average of 85 lbs (30.3%) over 104 weeks 45.3% of patients taking the maximum 12 mg dose lost 30% or more of their starting body weight a result normally seen after weight loss (bariatric) surgery The study also found significant improvements in key markers for metabolic syndrome, such as waist circumference, blood pressure, and harmful blood fats such as triglycerides and non-HDL cholesterol How does retatrutide compare to other weight loss medications

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These may occur with or without pain, and, as with other injection site reactions, usually go away on their own within a few days

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Potential expanded applications As the development of GLP-1 patches is underway, many companies are working to determine accurate dosing and obtain FDA approval for their transdermal GLP-1 patches

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