The concept of "best time to apply" becomes less about pharmacokinetic optimization and more about practical convenience and skin site rotation
Average copay ranges from $25 (Tier 2) to $290 (Tier 3) after approval
2010;376(9741):594 and 2010;376(9750):1392]
Full reconstitution guide Advanced calculator Dosing & Reconstitution Guide IU-based subcutaneous dosing on a U-100 insulin syringe, step by step Standard Protocol (2.0 mL = 2,500 IU/mL) Reconstitute: Add 2.0 mL bacteriostatic water to one 5000 IU vial final concentration 2,500 IU/mL
The weight gain that occurs if treatment is stopped may be dramatic compared to what might be expected from individuals not taking the medication, with associated increases in mortality risk throughout the duration of the policy
1 Remove Melanotan I vial from refrigeration and allow to reach room temperature (1520 minutes) 2 Clean vial top with alcohol swab and allow to air dry completely 3 Using a sterile syringe, draw the calculated volume of bacteriostatic water (BAC water) 4 Inject BAC water slowly down the side of the vial do not aim directly at the powder 5 Gently swirl in circular motions DO NOT shake vigorously as this degrades the peptide 6 Allow 23 minutes for full dissolution solution should be clear and colorless 7 Draw calculated dose into an insulin syringe for subcutaneous injection 8 Inject into abdomen, thigh, or upper arm
