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1 Introduction Hypothyroidism is a prevalent endocrine disorder defined by inadequate synthesis or secretion of thyroid hormones, primarily thyroxine (T 4) and triiodothyronine (T 3) (McDermott, 2020)

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Such change in male mice may contribute to metabolic sex dimorphism ( MUP1 mRNA levels were restored in CRY/ male mice with the injection of bovine GH and octreotide (to inhibit endogenous GH secretion)

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