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Even though kava is still readily sold as a dietary supplement, the FDA states that it is not generally recognized as safe (GRAS)

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10.1038/ncomms5386 261 YaoX.XianX.FangM.FanS.LiW

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Signals for disease modification Evidence for true disease modification remains low-certainty and hypothesis-generating, with recent observational signals serving as a foundation for potential disease modification rather than established therapeutic benefit (100)