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In the process of ascending through the cell layers of the epithelium to the surface desquamating layer, melanosomes lost from keratinocytes that form part of the melanocyte-keratinocyte unit disintegrate, releasing melanin dust into the microenvironment

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In lipid synthesis, fatty acids initially react with glycerol-3-phosphate to produce 1-acylglycerol-3-phosphate (LPA) in a reaction catalyzed by glycerol-3-phosphate acyltransferase (GPAT)