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Primary bile acids such as cholic acid and chenodeoxycholic acid are converted by intestinal bacteria into secondary bile acids, such as deoxycholic acid and lithocholic acid

Engineering strategies, including systematic evolution of ligands by exponential enrichment optimization, structural engineering, chemical modification and artificial base incorporation as well as advanced conjugation and delivery, have been employed to obtain FNAs with potential for biomedical applications such as targeted drug delivery, precise gene regulation, sensitive molecular diagnostics and multifunctional theranostics

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Dosing errors are the most commonly reported issue

A GP (General Practitioner) cannot initiate the treatment, although they can prescribe in very limited circumstances, e.g