Signs of inadequate dosing include return of food cravings, portion sizes increasing back to pre-treatment levels, and gradual 1 to 2 pound monthly weight increases
Biological Explanations and Clinical Implications These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones, says Jena Shaw Tronieri, Senior Research Investigator at Penns Center for Weight and Eating Disorders and a co-author of the study
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For most patients, gastrointestinal side effects are most pronounced in the first two to eight weeks of treatment and improve substantially as the body adjusts
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