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Community doses of 20-80 mcg daily are extrapolated from animal research scaling, decades of bodybuilding experience, potency considerations, and risk management balancing anabolic effects against hypoglycemia (Florini et al., 1996)

In these settings, sustained ROS overproduction drives HSC activation, fibrogenesis, genomic instability, and ultimately hepatocarcinogenesis

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This time point was included because primary HDFs exhibit a longer doubling time (Moulin et al., 2011

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