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Phase 2 data showed up to 60% of participants at higher doses reported at least one gastrointestinal symptom

As pharmacists and plan advisors, we typically suggest that plans not cover these drugs for weight loss alone

No causal link has been established in humans for retatrutide or other GLP-1-based medicines

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Body composition measurements provide the most meaningful long-term data

(59), peripheral administration of PP attenuates food intake and gastric emptying, while icv injection of PP increases food intake and delays gastric emptying, but it is not excluded that PP effects on food intake are secondary to changes of gastric emptying (59)