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doi: 10.1186/s10194-019-0993-0 2

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The epidermal growth factor receptor family: biology driving targeted therapeutics

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HSPA5/GRP78/BiP The accumulation of unfolded or misfolded proteins in the ER activates a signaling pathway known as the unfolded protein response (UPRER), which is regulated by three main sensors: protein kinase RNA-like ER kinase (PERK), inositol-requiring enzyme 1 (IRE1), and activating transcription factor 6 (ATF6)

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There is another little thing about him which cannot be overlooked

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These procedures help improve the skins texture and discoloration and enhance its beauty

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Barcelos RP, Stefanello ST, Mauriz JL, Gonzalez-Gallego J, Soares FA

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