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Because the final updates to the conversion factor (including the update of the OPD fee schedule increase factor), the estimated cost of the rural adjustment, and the estimated cost of projected pass-through payment for CY 2026 are applied uniformly across services, observed redistributions of payments in the impact table for hospitals largely depend on the mix of services furnished by a hospital (for example, how the APCs for the hospital's most frequently furnished services would change), and the impact of the wage index changes on the hospital

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Past and ongoing trials have tested therapies targeting inflammatory signalling (IL-1 receptor antagonist, TNF- inhibitor, and toll-like receptor-4 [TLR-4] inhibitor)