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It is not approved by the FDA for clinical use

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As a key coenzyme in mitochondrial energy metabolism, increased NAD enhances mitochondrial oxidative phosphorylation, promotes triglyceride breakdown in adipocytes, and converts fat into energy for the body, thereby reducing adipose tissue accumulation

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In contrast to monothiols, addition of the dithiol DTT to WT completely inhibited roGFP2 re-oxidation