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(2) As a result, over time, patients can eat less without feeling hungry or unsatiated

Mechanisms involve stimulation of VEGF and hepatocyte growth factor production along with activation of the Wnt/beta-catenin signaling pathway that drives follicle proliferation

doi: 10.3389/FMATS.2018.00019 186 van SeventerJ

It's about correcting the hormonal dysregulation (leptin resistance, ghrelin elevation, insulin resistance) that keeps the body in a fat-storage state despite caloric restriction

While there may be similarities between these molecules based on one of these factors, the use of all three data points can be utilized to distinguish and differentiate biochemicals