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However, due to their mechanism of action, primarily appetite suppression, GLP-1 analogs have been associated with various adverse effects
Bramham CR, Southard T, Ahlers ST, Sarvey JM (1998) Acute cold stress leading to elevated corticosterone neither enhances synaptic efficacy nor impairs LTP in the dentate gyrus of freely moving rats
[DOI] [PubMed] [Google Scholar] 164.Kakde D, Jain D, Shrivastava V, Kakde R, Patil A
Naunyn Schmiedebergs Arch Pharmacol
For maximum GH response with preserved pulsatility, the combination is generally preferred
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