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High levels of melatonin would be beneficial for the oocyte, as it helps in clearing free radicals, upregulates the antioxidant enzymes and even prevents apoptosis of the oocyte (186)

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These experiments confirmed that cagrilintide is a potent dual agonist, activating both receptor types, which is crucial for its therapeutic effect on reducing food intake and body weight, as demonstrated in preclinical rat models