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Glucoregulatory effect of recombinant 6mGLP-1 in type 2 diabetic mice models

Studies Vitamin A deficiency and alterations in the extracellular matrix

10.3390/ijms25126585 104 ZhangS

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They result in modest improvement in HbA 1c , with a reduction of around 0.51.0% when used as monotherapy and around 0.61.1% when used in combination with metformin, depending on the agent, dose of therapy and starting HbA 1c