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Indeed, the history of anti-obesity medications has been marked by several failures due to serious adverse events, such as suicidality, observed only after their usage had become extensive 221,234 a well-known example being the one that led to the withdrawal of the endocannabinoid inverse agonist, rimonabant 235

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Your appetite drops dramatically, and weight comes off fast

Some patients believe they can find their own ideal dose through trial and error, starting low and adjusting as needed

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For more than 25 years, attempts to import unauthenticated foreign medicines to lower costs have repeatedly failed and posed serious public health risks