semaglutide eli lilly Tirzepatide Tops for Weight Loss in Head-to-Head Trial, Says Hims stock plunges as Lilly's

N Engl J Med 384(11):9891002 Horn DB, Kahan S, Batterham RL et al Time to weight plateau with tirzepatide treatment in the SURMOUNT-1 and SURMOUNT-4 clinical trials

Peer-reviewed data on optimal maintenance dosing remains limited, though real-world registry analyses suggest that partial dose reduction can retain 70 to 80% of weight loss in selected patients

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Wiegand S, Keller K-M, Lob-Corzilius T, et al

A 2-way ANOVA was used to compare differences between GLP-1(2836) and the scrambled control across multiple doses or different mouse strains