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Interestingly, GIP has been shown to stimulate glucagon secretion even with high glucose in T2D patients, which implies that inappropriate GIP/GIPR activity contributes to the T2D disease phenotype

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However, if we accept that addictive disorders are fundamentally characterized by psychological dependence and negative consequences, it becomes clear that addiction is not confined to the consumption of chemical substances

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Biotechnol Prog 20:449456 Drge W, Breitkreutz R (2000) Glutathione and immune function