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By 6 weeks, there were already measurable decreases in both the intensity and size of these spots

The 2004 Bissett study in International Journal of Cosmetic Science used twice-daily 5 percent niacinamide for 12 weeks in 50 women aged 40 to 60, documenting significant reductions in fine lines, hyperpigmentation spots, blotchiness, and yellowing [13]

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[26] recently observed an increase in ASD associated with the postnatal use of APAP in the DNBC

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