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Amyloid protein aggregates can also form cytotoxic oligomers, destroy the integrity of the cell membrane, and further aggravate islet damage [249, 250]

Quercetin Stimulates Bone Marrow Mesenchymal Stem Cell Differentiation through an Estrogen Receptor-Mediated Pathway

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In DKD, ERS is primarily triggered by hyperglycemia, proteinuria, and the presence of AGEs and free fatty acids ( A recent study has revealed that ERS can increase the levels of unsaturated triacylglycerol precursors and reduce lipid droplet formation, leading to tubular injury and fibrosis in renal proximal tubular cell lines and STZ-induced diabetic mouse kidneys (83)

But it could also mean you have growths like fibroids or polyps in your uterus

You can view all of the tests I recommend in my article on SIBO