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69% have been using the medication for fewer than two years and 53% expect to discontinue use in less than two more years 77% who had discontinued a GLP-1 medication said they were satisfied with the weight loss they experienced, but 90% were on the drug for less than one year Primary barriers to continued use: 76% note side effects

Additionally, NSAIDs can affect kidney function by reducing renal blood flow, particularly in patients with pre-existing kidney disease, dehydration, or those taking other medications that stress the kidneys

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Nature 566 , 115119 (2019)

New Test Detects the 'Invisible' Performance Peptide CJC-1295 in Horse Blood. Drug testing and analysis.Study breakdown PubMed

Admittedly, the lesser potency of these drugs in the initial weight loss phase often overshadows their potential for usage for weight loss maintenance purposes