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This was particularly evident in the mitochondrial proteins responsible for detoxifying H 2 S, and this downregulation was associated with a higher disease severity (70)

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GSH's biological activity depends on this thiol function

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SLC31A1 is significantly correlated with diverse immune cell infiltrations, immune cell biomarkers, and immune checkpoints in breast cancer and is regulated by the LINC01640/miR-204-5p/SLC31A1 axis, which may be central to copper-induced cell death in breast cancer, suggesting that SLC31A1 may serve as a potential target for adjuvant immunotherapy [103]