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Similarly, patients who have required hospitalization or biologic immunosuppressant therapy (such as TNF inhibitors) within the past year should exercise extreme caution, as their disease is less stable and their gut barrier may be more vulnerable to treatment-induced stress

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With the stakes so high, companies are chasing these outcomes in the billion dollar GLP-1 market, trying to figure out whether their genetic models can determine which GLP-1 someone should take, predict how much weight they might lose, whether they experience side effects and what happens after treatment stops

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Hyposecretion of cortisol is known as adrenal insufficiency

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