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Once acyl-carnitine is inside the mitochondrial matrix CPT II separates it into L-carnitine and acyl-CoA

Curcumin reverses the sunitinib resistance in clear cell renal cell carcinoma (ccRCC) through the induction of ferroptosis via the ADAMTS18 gene

The MT1 and MT2 melatonin receptors differential affinities account for their categorization

Regulation of glutathione synthesis by cadmium in Pisum sativum L

Unlike many pharmaceuticals that have linear pharmacokinetics, fenbendazole exhibits saturable first-pass metabolism meaning that beyond a certain dose threshold, the liver's capacity to process the drug becomes overwhelmed, leading to disproportionately higher systemic exposure

PLoS ONE 6 , e22640 (2011)