At peripheral levels, the administration of GLP-1 RA regulates follicular proliferation and apoptosis-induced follicular atresia of the granulosa cells, a key component of the dominant follicle selection, possibly contributing to the oocyte maturation in PCOS
D., Satylganova, A., Skovgaard, D., Sugimoto, D., Jensen, C., & Mosenzon, O
Use of twice-daily exenatide in Basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial
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In pancreatic cells, activation of these G proteincoupled receptors primarily signals through pathways involving cyclic adenosine monophosphate (cAMP), protein kinase A ( PKA ), and cAMP response elementbinding protein ( CREB ), thereby enhancing glucose-dependent insulin secretion and supporting -cell function