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Description

2023;148(9):e9-e119

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Retatrutide is more accurately described as a triple receptor agonist research compound involving GLP-1, GIP, and glucagon receptor pathways

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Managing Lower GI Issues: Constipation & Bloating The most common complaint on these medications is severe constipation

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These are more likely to occur within the first weeks of initiation of therapy and with dose escalation

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Lifestyle habits play a meaningful role in managing both diabetes medications and anticoagulant therapy

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Phase 2: Larger trials measure weight loss and side effects

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