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In the United Kingdom, approximately 5.2 million adults (7.7%, aged 18-74) and 2.5 million children (18%, aged 0-17) are affected by moderate or severe atopic dermatitis, also known as atopic eczema

Both options can be prescribed by licensed clinicians

What to Expect in Months 7-11 Essentially no side effects: Appetite suppression continues (desired effect), but GI symptoms gone Weight loss velocity slows: From 0.8kg/week (months 3-6) to 0.3-0.5kg/week Plateau around week 40-48: Weight stabilizes, no longer losing despite continued medication Total weight loss: Average 20-24% from baseline (matching or exceeding surgical outcomes) Focus shifts to maintenance: Accepting current weight, preventing regain Plateau frustration: Not a side effect but an emotional challenge 2 Final Strategies for Months 7-11 20

More recently, Arbabi et al.[38] demonstrated the effect of both GLP-1 and Ex4 in an experimental model of steroid-treated ovariectomized ewes

Thousands of researchers go through this exact moment, needle in hand, heart rate climbing, confidence dropping

doi: 10.1056/NEJMoa2108269