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Upon delivery into the failing myocardium, the CaP shell decomposes and TP-10 is released, which can effectively attenuate cardiac remodelling and improve cardiac function
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PBMs have responded to gene therapies through a combination of prior authorization requirements (which serve as the primary utilization management tool), outcomes-based payment arrangements with manufacturers, and in some cases, carve-out arrangements where gene therapy coverage is managed separately from the standard pharmacy benefit
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UC is characterized by frequent bloody diarrhea, pain, fatigue, and progression, and more than 1/3 of patients require hospitalization or surgery
Insulin-like Growth Factor-1 Long Arginine 3, or IGF-1 LR3, is a modified, long-acting analogue of endogenous IGF-1
