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A major consideration is the choice between a short-acting and a long-acting GLP-1 RA

The FDA flags many research compounds with limited human safety data

Richards M et al

Do not use if the vial is damaged, the seal is broken, or the material shows unexpected discoloration or contamination

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Patients wishing to understand their eligibility for NHS weight management services, including Tier 3 specialist services or Tier 4 bariatric surgery pathways, should speak to their GP, who can advise on local referral criteria in line with NICE and NHS guidance