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For instance, two siblings both harboring the same mitochondrial mutation causing Lebers hereditary optic neuropathy had markedly different clinical courses: the brother exhibited typical progressive optic neuropathy whereas the sister suffered from a relapsingremitting MS-like illness (Joshi and Kermode, 2019)

Nayan Patel [00:12:09]: So that's one thing that is abundantly known everywhere

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But if youre tired and theres no other underlying problem causing it, the likelihood is you probably need to rest.

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McInnes G, Evans M, Del Prato S, Stumvoll M, Schweizer A, Lukashevich V, Shao Q, Kothny W