Furthermore, the United States Food and Drug Administration (FDA) has explicitly and formally warned that compounded injectable drugs containing GHK-Cu present significant risks for severe immunogenicity
These results were most significant in women with a BMI great than 30, taking at least 1,000mg daily for at least three months
An open-label study (n=42) found that IV NAC (50 mg/kg) combined with oral NAC (500 mg twice daily) for 3 months increased brain glutathione levels (measured by MRS), increased dopamine transporter binding (measured by DaTscan), and improved UPDRS motor scores (Monti et al., PLoS One, 2016) [53]
Maybe even a better situation because it's a natural substance that's in your body that we're just augmenting
The journey toward an optimal oral GLP-1 is exemplified by the contrasting fates of Pfizers danuglipron and Eli Lillys orfoglipron
However, tesofensine, being a pharmaceutical intervention, may carry certain risks