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Although leg cramps are not listed as an official adverse effect in FDA prescribing information, understanding the potential indirect mechanismsincluding dehydration, electrolyte imbalances, and nutritional changescan help patients and clinicians address this symptom effectively while continuing therapy

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The 55-year-old patient rocked up to hospital complaining of a 'painful, sustained penile erection' which had been going strong for 30 hours by the time he arrived