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Several other trials are assessing the safety and efficacy of tirzepatide in improving different cardiometabolic complications such as OSA, MASH and heart failure with preserved ejection fraction (HFpEF) (NCT05412004, NCT04166773, NCT 04847557) [16]

The protective effect for diabetes is promising and may help with treatment decisions in the future

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However, unlike Ozempic, Wegovy is FDA approved for weight management in adults with overweight and obesity and children ages 12 years and older with obesity