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Fibrogenesis Tissue Repair 5:11

found that accumulation of iron and ROS, dysfunction of iron metabolism, decreased GPX4 activity, and mitochondrial atrophy after TBI are all typical characteristics of ferroptosis

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Given that the effectiveness of NAC for treating APAP-induced liver injury is confined to modest improvements within a brief period after onset and considering that high doses of NAC can potentially negatively impact hepatocyte metabolism and liver regeneration (Jaeschke et al

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