Disruption of Vesicular Storage (VMAT2): Once inside the neuronal cytosol, amphetamine is taken up into synaptic storage vesicles (predominantly those in a finite readily releasable pool ) via the vesicular monoamine transporter 2 (VMAT2)
The FDA prescribing information does not list hepatotoxicity as a known adverse effect, and extensive clinical trial data have not identified significant liver-related safety signals
For me, I knew I didnt want to rely on medication forever, nor did I want that financial burden forever
Brand-name Wegovy without insurance runs about $499 a month for the medication alone
This mechanism slows gastric emptying, increases feelings of fullness, and reduces appetite through brain signals, not stimulation
doi: 10.1016/s1093-3263(98)00002-3 18 HossainM