Berberine can interact with numerous medications through inhibition of certain liver enzymes (CYP3A4, CYP2D6, CYP2C9) and transport proteins (P-glycoprotein)
The final rate-limiting enzyme -BBH is highly active in the small intestine
The choice between them depends on whether a researcher prefers a single-compound approach or a combination protocol
It can be hard to recognize a B12 deficiency, as the symptoms can be vague and are primarily cognitive
doi: 10.3390/molecules30061190
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