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In a European multi-center clinical study, supplementation with L-carnitine (in the form of propionyl-L-carnitine at 2 g/day for 12 months) in patients with moderate to severe claudication related to the maximum distance covered and the perceived quality of life achieved a significant improvement compared to patients who received only placebos

Studies examine the peptide's ability to maintain endothelium integrity and modulate vascular tone

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The results are better when it is combined with vitamin C than with internal or injectable forms