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Weight loss reduces metabolic rate and subcutaneous fat insulation, leading to increased cold sensitivity through adaptive thermogenesis

The treatment duration should be tailored to achieve and maintain the desired weight loss while ensuring patient safety

Evidence from combination studies reinforces findings from studies on individual medications, indicating that most adverse effects are transient and frequent ones are easily managed

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Chao explained that compounded pills might be mixed by hand in small batches without stringent bioequivalence standards