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In new research from Stefano Comai et al., mice who were genetically altered to have no M1 receptor (MT1KO knockout mice) showed a decrease in rapid eye movement (REM) sleep, which is linked to dreaming, and an increase in slow wave (or deep) sleep

While the procedure is generally well-tolerated, mild discomfort, bruising around the IV site, or slight vein inflammation may occur

Efficacy and safety of lixisenatide once-daily versus placebo in patients with type 2 diabetes mellitus insufficiently controlled on met-formin (GetGoal-F1) [Abstract] Diabetologia

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Zigouras, S., et al., Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats

Conclusion NNMT inhibition, including with 5-Amino-1MQ, is a rapidly evolving research area