For comparison, the Summaries of Product Characteristics (SmPCs) for approved weekly GLP-1-based therapies including semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro), available via the electronic Medicines Compendium (emc) do not specify a preferred time of day for injection
This reduced caloric intake semaglutide creates a calorie deficit, which can cause you to experience fatigue or feel tired as your body adapts
Oral options are emerging quickly, including oral semaglutide formulations and orforglipron, marketed as Foundayo
Avoid tight clothing around the injection site
Jessica Migala Author Jessica Migala is a freelance writer with over 15 years of experience, specializing in health, nutrition, fitness, and beauty
Some people feel more tired than usual on the day of injection, and this can be amplified when dosing early