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Quality assessment of evidence We used the Cochrane randomised trial Risk of Bias tool (version 2.0) to assess the risk of bias in the included trials, including random sequence generation, assignment hiding, blinding, loss of result data, and selective reporting of results

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GLP-1 medications like semaglutide function by slowing gastric emptying and signaling satiety to the brain

Delayed emptying raises acid levels GLP-1 drugs slow gastric emptying, causing food and acid to remain longer

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