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We define reparative fibrosis as the formation of an organized fibrotic tissue that helps to mechanically stabilize the degenerating tissue defect

There may be a number of sources of this oxidative stress, including mitochondrial superoxide production, ischemia-reperfusion mechanisms and auto-oxidation of catecholamines

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Key factors hindering the healing of diabetic wounds include persistent high level of reactive oxygen species (ROS), excessive inflammatory cells and cytokines in the wound microenvironment, insufficient new blood vessel formation, and weakened cell proliferation 21,22

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This depends on your deficiencys severity, health, and how you respond to treatment