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Blocking IL-23 results in a downstream block of IL-22 and pathogenic Th17 cells involved in bone loss pathogenesis

Plotted in red is the unweighted UniFrac distance between consecutive microbiome samples for all participants

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L-carnitine modified nanoparticles target the OCTN2 transporter to improve the oral absorption of jujuboside B

Participants lost an average of 16.6% of their body weight, a significant improvement compared to just 3.2% in the placebo group