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By constantly signaling to the brain that the body is full, peristalsis (rippling GI waves that push contents through the gut) is slowed, thereby disrupting the bodys natural digestion process. According to Fereday: The anecdotes of the early adopters are not necessarily that representative of how things will play out if this class of drugs goes mainstream

Exercise Timing Light to moderate exercise during the first 3 months supports results without overwhelming the body during adaptation

Symptoms of depression or persistent low mood alongside changes in desire

The first three months are the adjustment period

For example, if someone has ongoing nausea, it can lead to less fluid intake for several days

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