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Our results provide a framework for understanding GHSR signaling and developing new GHSR agonist drugs

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This study was an observational cohort investigation using electronic health record data from the United States Department of Veterans Affairs and included 606,434 patients with type 2 diabetes who newly started either a GLP-1 medication or, as a comparator, a sodium-glucose cotransporter-2 inhibitor (a type 2 diabetes medication that doesnt affect appetite and reward pathways) based on filled outpatient pharmacy records

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Key players in the market include Novo Nordisk, Eli Lilly, Sanofi, Boehringer Ingelheim, AstraZeneca, Merck & Co., Bristol-Myers Squibb, and Amgen