Certain diets, some medications, older age, and absorption conditions raise the risk of deficiency
Tiny bumps on your tongue called papillae start to waste away
Although folic acid absorption by the intestine is catalyzed by the proton-coupled folate transporter (PCFT), which has similar affinity for both folic acid and reduced folates ( Table 2 ) (65, 66), the affinity for folic acid of the reduced folate carrier (RFC), which is ubiquitously expressed in all tissues, is 50- to 150-fold lower than that for 5-methylTHF and other reduced folates (Table 2) (65, 66)
Is it normal for symptoms to initially worsen before improving with B12 therapy
These injections bypass the digestive system and deliver the vitamin directly into your bloodstream, allowing for rapid correction of the deficiency and improvement in symptoms like fatigue
Prescription Requirements and Medical Supervision First, you need a doctors prescription for B12 injections